To maximise the power of Mental Misstep in a deck you are advised to have some filer and/or card quality effects so that you can replace it once its value is diminished
While it is niche - there needs to be a reason to have this in a Tron or Eldrazi sideboard, for instance - when it's powerful, it's really powerful
Similarly, the "Second Generation Sets" published by Wizards comprised "Neo Genesis", "Neo Discovery", "Southern Islands", "Neo Revelation", "Neo Destiny", "Legendary Collection", "Expedition Base Set", "Aquapolis", and "Skyridge"
This differs from the original Mardu way that included rules and honor
Some squirrel decks hang back and wait to assemble their combos, but a double helping of myriad really points toward turning a bunch of cardboard sideways