PE133000: α-GalNAc-PEG3-Amine label-new H-Thr(β-GlcNAc)-OH

H-Thr(β-GlcNAc)-OH

(Xylα(1-4)GlcA)-β-O-4-MU

β-D-GalNAc-Bu-COOH

/ AHSG-2-bovine(334−348)-Tn(341) / Synthetic Fetuin-A non-glycosylatedpeptide

/ DAG1(371-383)-Man(379) / Dystroglycan1

PE133000: α-GalNAc-PEG3-Amine label-new H-Thr(β-GlcNAc)-OHC14H28N2O8 352. 38 An D N acetylgalactosamine (GalNAc) ligand equipped with a primary amine through a hydrophilic PEG3 spacer. The amine couples with NHS activated esters to form stable amide bonds, providing a route to conjugate the ligand onto NHS activated molecules and surfaces. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR), which is highly